Platform

Objective characterization of subretinal delivery

Our AI-assisted platform converts existing surgical video into quantitative measures of instrument behavior during the critical delivery maneuver. No additional intraoperative hardware is required.

What we measure

Precision

How steadily and precisely the cannula or instrument tip remains during the critical maneuver.

Smoothness

How fluid the instrument trajectory is, rather than abrupt, jerky, or corrective.

Instability

Abrupt or outlier motion events that may alter local delivery dynamics.

Tremor

Oscillatory motion within defined frequency bands during controlled cannula positioning or delivery.

Supporting measure

Recovery / repositioning activity

Small recovery or repositioning movements around the delivery maneuver.

Together, these measurements characterize how the delivery maneuver unfolds and can be interpreted in the context of anatomy, device, procedure, imaging, safety, and clinical outcome.

What these measurements can be compared with

DexteraAI measurements can be analyzed against sponsor-defined procedural and clinical endpoints, including reflux, retinotomy behavior, bleb formation, delivery success, procedure-related adverse events, imaging findings, visual outcomes, durability, and rescue-treatment burden.

Applications

How DexteraAI can be applied across development

Retrospective analysis is the current offering; later applications depend on validation and sponsor needs.

Current

Retrospective Phase 1/2 or Phase 2 analysis

Evaluate whether delivery characteristics are associated with sponsor-defined procedural, safety, imaging, or clinical endpoints.

Potential future

Prospective consistency monitoring

Track whether validated delivery characteristics remain stable across surgeons, sites, cases, and time.

Potential future

Interpretation of heterogeneous outcomes

Apply validated procedural biomarkers to help explain variation in efficacy, safety, or durability.

Potential future

Surgeon support and launch

Use validated insights to support onboarding, training, workflow refinement, and post-market monitoring.

Patent-pending AI-enabled surgical video analytics for subretinal therapeutic trials.