Trial Focus

Subretinal therapeutic trials in retina

Focused on the critical subretinal delivery maneuver, where technical performance is especially consequential.

How it works

Surgical video

Routine delivery footage you already capture.

Objective motion analysis

Mapping precision, smoothness, instability, and tremor.

Clinical-trial quality-control report

A sponsor-facing read, aligned to your procedural and clinical endpoints.

Who we serve

Retinal gene and cell therapy programs requiring subretinal delivery

DexteraAI's initial focus is retinal gene and cell therapy programs requiring subretinal delivery. These trials involve high-value biologic products, technically demanding surgical administration, and narrow regulatory and adoption pathways because established intravitreal therapies already exist for major retinal diseases.

  • Multi-site, multi-surgeon subretinal therapeutic trials
  • Programs where reflux, retinotomy behavior, bleb behavior, or delivery consistency may affect interpretation
  • Sponsors seeking objective measures of surgeon/site technical consistency
  • Retrospective Phase 1/2 or Phase 2 analyses before pivotal expansion
  • Post-hoc interpretation of heterogeneous pivotal-trial outcomes

Schedule a Technical Briefing

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Use Cases

How DexteraAI is applied across the trial lifecycle

Four applications spanning pre-pivotal analysis through post-market surgeon quality assurance.

Before pivotal

Retrospective Phase 1/2 or Phase 2 analysis

Evaluate whether delivery-performance metrics are associated with sponsor-defined procedural, safety, imaging, or clinical endpoints.

During pivotal

Prospective surgeon/site consistency monitoring

Track whether technical-performance profiles remain stable across surgeons, sites, cases, and time.

After pivotal

Interpretation of heterogeneous outcomes

Assess whether surgical technical variability may have contributed to efficacy, safety, or durability variability.

Launch

Surgeon training and quality assurance

Support objective, video-derived feedback for surgeon onboarding, credentialing, retraining, and post-market monitoring.

Is your program in this space?

If you're developing a subretinal therapy and thinking about surgical variability, we'd like to hear about it.